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Ph-Interfering Agents as Chemosensitizers in Cancer Therapy: Volume 10

Ph-Interfering Agents as Chemosensitizers in Cancer Therapy: Volume 10 - Hardcover

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Availability:In StockContributor:Claudiu T. Supuran, Simone CarradoriSeries:Cancer Sensitizing Agents for ChemotherapyPublish date:9/3/2020Pages:228
Languages:EnglishPublisher:Academic PressISBN-13:9780128207017ISBN-10:0128207019UPC:9780128207017Book Category:Science, MedicalBook Subcategory:Life Sciences, OncologyBook Topic:BiologySize:9.25 x 7.50 x 0.56 inchesWeight:0.613Product ID:SCF4FHJ79A

pH Interfering Agents as Chemosensitizers In Cancer Therapy, Volume Thirteen, provides a detailed overview of the chemosensitizers for the treatment of cancer spanning from biochemical and structural features to pharmacology and drug-design, including technological applications. The book is structured with innovative outlines and a distinction between experimental and clinical results. The continuous discovery and assessment of the role played by old/new synthetic drugs, natural compounds and technological applications has led to the urgent need of classification in terms of biological activity, mechanism of action, clinical outcomes, cancer cell lines sensible to the treatment, and potentialities to better orient research in this field.

Moreover, all the aspects relevant for medicinal chemistry (drug design, structure-activity relationships, permeability data, cytotoxicity, appropriate statistical procedures, and molecular modeling studies) are strictly considered.

Languages:EnglishPublisher:Academic PressISBN-13:9780128207017ISBN-10:0128207019UPC:9780128207017Book Category:Science, MedicalBook Subcategory:Life Sciences, OncologyBook Topic:BiologySize:9.25 x 7.50 x 0.56 inchesWeight:0.613Product ID:SCF4FHJ79A
Carradori, Simone: - Dr. Carradori is a very prolific researcher with papers dealing with both synthetic and natural products characterized by promising biological activities. Regarding this topic, he has been involved in the study of HAT inhibitors, hCA IX and XII inhibitors, kinesin Eg5 inhibitors and natural compounds active in the field of oncology. Recently, he has been focusing on "drug repurposing" disclosing a patent on new roles played by antiparasitic benzimidazoles as anti-cancer agents. He also was Co-Guest Editor of several special issues, co-author of chapters for two books (one edited by Elsevier) and acts as Editorial Board member of several peer-reviewed journals.Supuran, Claudiu T.: - Dr. Claudiu T. Supuran received his BSc in chemistry from the Polytechnic University of Bucharest, Romania (1987) and PhD in chemistry at the same university in 1991. In 1990, he became Assistant and then Associate Professor of Chemistry at the University of Bucharest. He was Visiting Scholar at the University of Florida, Gainesville, United States, at Griffith University, Brisbane, Australia, and Visiting Professor at University of La Plata, Argentina. In 1995 he moved to the University of Florence, Italy, where he is currently Full Professor in the Department of Neuroscience, Psychology, Medicine and Child Health. His main research interests include design of enzyme inhibitors and activators, heterocyclic chemistry, chemistry of sulfonamides, sulfamates, and sulfamides, biologically active organo-element derivatives, QSAR studies, X-ray crystallography of metallo-enzymes, metal complexes with biologically active ligands (metal-based drugs), carbonic anhydrases, cyclooxygenases, serine proteases, matrix metalloproteinases, bacterial proteases, and amino acid derivatives among others. He has published more than 1900 papers in these fields.
Publisher: Academic Press

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