Artificial Metalloproteins: Volume 720 - Hardcover
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Availability:In StockContributor:Lisa OlshanskySeries:Methods in EnzymologyPublish date:10/31/2025Pages:412
Languages:EnglishPublisher:Academic PressISBN-13:9780443415739ISBN-10:0443415730UPC:9780443415739Book Category:ScienceBook Subcategory:Life SciencesBook Topic:Biochemistry, Molecular BiologySize:9.21 x 6.11 x 1.11 inchesWeight:0.863Product ID:SCDGGSER7H
Artificial Metalloproteins covers artificial metalloproteins (ArMs) and how they have emerged as powerful vehicles with which to control, implement, and leverage the unique reactivity and spectroscopic properties of their bound metal ions. Chapters in this release include Incorporating Non-Native Cofactors into Heme Proteins, Designing 4-Helix Bundles to Bind Porphyrin/Porphyrin-like Cofactors, Cobalt-Substituted Hemoprotein Expression, Rationally designed directed evolution of cytochrome P450 enzymes, De novo design of a switchable a-helical hemoprotein, Primary Coordination Sphere Part B: Unnatural Metal-Binding Sites Beyond the Heme, and more. Other sections cover Unnatural Amino Acid Incorporation for Creating Artificial Metalloenzymes, Development of a PQQ-Dependent Artificial Metalloprotein, Evolutionary Engineering of a Rhodium Complex-Linked Artificial Metalloenzyme, Design and Application of Nonheme Iron Enzymes, Part C: Secondary Sphere Modulation for Metallocofactor Activation, Designing Artificial Metalloenzymes by Engineering the Primary and Secondary Coordination Sphere in Native Protein Scaffolds, and much more.
Languages:EnglishPublisher:Academic PressISBN-13:9780443415739ISBN-10:0443415730UPC:9780443415739Book Category:ScienceBook Subcategory:Life SciencesBook Topic:Biochemistry, Molecular BiologySize:9.21 x 6.11 x 1.11 inchesWeight:0.863Product ID:SCDGGSER7H
Olshansky, Lisa: - After earning her B.S. in Chemistry from UC San Diego in 2009, Dr. Lisa Olshansky completed her Ph.D. in Chemistry at MIT in 2015 as an NSF Graduate Research and Presidential fellow under the mentorship of Profs. Daniel Nocera and JoAnne Stubbe. She then went on to work with Prof. Andy Borovik at UC Irvine as an ACS Irving S. Sigal Postdoctoral fellow. In 2018, Lisa began her independent career as an Assistant Professor of Chemistry at the University of Illinois, Urbana-Champaign where her team is working to mimic and exploit mechanisms by which macroscopic molecular structural changes dictate metal ion electronic structural properties. During her early career, Olshansky has been recognized with Searle, Cottrell, and Vallee Scholars awards, Carver Trust and DOE Young Investigator awards, and an NIH Early Stage Investigator award. Olshansky was recently named an NAS Kavli Fellow, received the Paul Saltman Young Investigator Award for her research on Metals in Biology, and was recently named a Camille Dreyfus Teacher-Scholar and a Sloan Research Fellow. Finally, since joining the faculty at Illinois, Olshansky has spearheaded an initiative called C2 that aims to foster inclusivity and diversity in the School of Chemical Sciences at Illinois.
Publisher: Academic Press
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